When there is no time for egg freezing, or a girl is not yet through puberty, ovarian tissue freezing may help. This page on fertility preservation in Pune explains how ovarian tissue is removed and frozen, who it may suit, how the tissue can later be returned to the body and what limitations exist, for families in Shivajinagar, Deccan, Aundh, Hadapsar and across the city.
Ovarian tissue freezing involves removing a piece of the ovary, or occasionally a whole ovary, by keyhole surgery and freezing thin strips of its outer layer, where immature eggs live. Later, the tissue can be thawed and grafted back, possibly restoring hormones and fertility. It is a specialised technique offered at a limited number of centres, and decisions often involve oncologists and fertility specialists together.
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| Method | Time needed | Suitable before puberty | Restores hormones |
|---|---|---|---|
| Egg freezing | About two weeks | No | No |
| Embryo freezing | About two weeks, needs partner or donor sperm | No | No |
| Ovarian tissue freezing | A single keyhole operation | Yes | Possibly, after reimplantation |
The surgery can often be combined with other procedures, such as placing a central line for chemotherapy.
When the woman is well and ready, strips are thawed and placed on the remaining ovary or in a pocket near it. Hormone function often returns after several months. Pregnancies have followed, both naturally and through IVF, though numbers worldwide remain modest.
For some cancers, especially leukaemia, there is a risk that cancer cells may be present in the ovarian tissue and could be reintroduced. Tissue is examined carefully, and reimplantation may not be advised in high-risk situations. Research into safer alternatives, such as growing eggs from tissue in the lab, is ongoing.
Grafted tissue may function for a few years, depending on how many follicles it contains. Women are usually encouraged to try for pregnancy while it is active.
Ovarian tissue freezing is offered by a small number of specialised centres. Couples and families may need to travel or coordinate with laboratories that have experience in tissue processing.
Laparoscopy for ovarian tissue freezing usually involves a short hospital stay or day care. Most girls and women recover within a few days, with mild shoulder or abdominal pain from the gas used during surgery. Because the procedure is often done just before chemotherapy, teams time it carefully so that wound healing does not delay cancer treatment. Removing part of one ovary leaves the remaining ovarian tissue to continue producing hormones until treatment affects it.
In some adult women, ovarian tissue freezing can be combined with collection of immature eggs from the removed tissue, which are then matured in the laboratory and frozen. Others may have tissue freezing followed by a rapid egg freezing cycle if time allows. Combining approaches may increase the total number of future options, though success rates for lab-matured eggs are still lower than for eggs matured in the body.
GnRH agonist injections during chemotherapy are sometimes used to protect ovarian function, particularly in women with breast cancer. Evidence suggests they may reduce the risk of early menopause in some groups, but they are not a substitute for freezing eggs, embryos or tissue when future pregnancy is important.
After treatment, regular checks of hormone levels and periods show how much natural ovarian function remains. This helps decide when, or whether, reimplantation is needed.
Pune's large hospitals and cancer centres can refer families to fertility specialists with experience in preservation. Ask the oncology team early, ideally at diagnosis, so all options can be discussed.
When time or age limits other methods, fertility preservation treatment options in Pune include ovarian tissue freezing, egg or embryo freezing where possible, ovarian protection discussions and future reimplantation planning.
When comparing fertility preservation clinics in Pune or a fertility preservation centre in Pune, look for experience with tissue freezing and close links with oncology. The best fertility preservation in Pune acts quickly without delaying cancer care. Fertility preservation doctors in Pune should explain safety limits, and a fertility preservation specialist in Pune will guide storage decisions.
Request a fertility preservation consultation in Pune through any profile listed. Bring the oncology treatment plan.
Ovarian tissue freezing can keep future fertility within reach for those who have no time to wait.
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Removing and freezing strips of ovarian tissue containing immature eggs for later reimplantation.
Girls before puberty and women who cannot delay cancer treatment for egg freezing.
Often yes, after several months, for a variable period.
There may be a risk of reintroducing cancer cells, so it may not be advised.
It usually requires only a single keyhole operation and can often be done quickly.